Pretend Friends Forever. used when two people act like they're great friends, but then bitch and spread rumors about each other behind their backs. typically used on females.
Kate: Aww girl I love you so much!
Molly: We're gonna be friends forever!

-hour later-

Molly to someone else: oh my god kate is such a whore!

*Someone who overheard both conversations*: damn, Molly and Kate are complete PFFs!
by theatrerocks1432 May 6, 2011
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Example of Disagreement:
Bill - I can fuck that hot chick!
Fred - pff!

Example of Agreement/as good as done:
Bill - we are going to get fucked up!
Fred - pff!

1.b. One may also choose to spell out pff for a more dramatic effect.

Example:
Example of Disagreement:
Bill - I am one cool dude!
Fred - P-F-F!
by Rick James February 25, 2005
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Platonic Friends Forever. 2 friends who have no desire to ever be romantically involved.
Jack and Jennifer are PFFs.

John and Sarah were PFFs from the time they met.
by bowl of cherries January 13, 2012
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• Verb
(P)ay (F)uck (F)ly.
The act of literally paying for a fuck before flying off.
Man I can’t be bothered to chat up a chick tonight, I’ve a flight to catch early in the morning. I’ll PFF it instead.
by Jayed January 26, 2018
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Pussy Fearing Faggot

A dude who would rather hang out with his boys than entertain the possibility of talking to females
Griff: The reason none of you want to come to my sister's party is cuz ur all a bunch of PFFs. Grow a schlong and come get some punani. Let me count the ways, or the number of bitches that ive laid.
by Chinese Takeaway July 28, 2009
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A type of Train, usually dealing with speed.
The PFF Express is rolling in tonight.
by Anonymosity December 30, 2008
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