PGR or "Prettiest Girl in the Room" Disease is a condition that afflicts attractive women everywhere. It's characterized by the negative reaction a pretty girl expresses when she meets a girl that's prettier than her, rendering her "not the prettiest girl in the room" anymore.
Girl 1: Mandy, you look lovely as always. I'd like you to meet my friend, Sexy Withoutmakeup.
Girl 2: I don't like her.
Girl 1: You just met her, why not?
Girl 2: She's dressed like a whore.
Girl 1: Oh, you're just being jealous. You've got PGR Disease.
Girl 2: I don't like her.
Girl 1: You just met her, why not?
Girl 2: She's dressed like a whore.
Girl 1: Oh, you're just being jealous. You've got PGR Disease.
by rhastings88 February 24, 2014