Guard Bitch Share definition Flag We all know that females travel in packs. The guard bitch is the ugly friend(s) that guard the hot girls from unwanted men. I went to the club the other night and i totally got cock blocked by a guard bitch! Guard Bitch by jxb December 29, 2008 0 0 Get merch Get the Guard Bitch mug. Buy Now — $32.95 See more merch