Is like saying that the son of god is a shit.
Actually the meaning is (Shit Jesus or Jesus is shit). Maybe not one of the most used ones but i
swear that is a good and
proper way to esclamate when something bad happens. Examples.
Apri la finestra che c'è puzza Gesù merda. (Open the
windows that the rooms stinks Jesus merda).
Stai zitto testa de cazzo che
hai rotto lo schermo Gesù merda. (Shut up dickhead, you
broke the screen Jesus merda).