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Term used the next day after having nasty sex all night with some Fuck Muppet.
Bill: Hey Joe, did you go out with Cindy Lou last night?
Tyrone:Yeh and she Gave It Up real good too.
by Mojo Maniac July 15, 2008
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What nerds and retards call losing their virginity.
Chick 1: So what did you guys do last night?
Chick 2: I gave it up to him.
Chick 1: You sound like a god damn retard when you say it like that.
by apfunction December 8, 2009
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One of the best ways to get out of something you don't want to do.

P.S. Only can be used for 40 days before easter.
"John, wanna go to the mall with me :D?" -Annoying ugly girl
"I gave it up for lent"-John
"Oh well in that case nevermind."-Annoying ugly girl

"Brian, take out the trash."-Your mom
"Sorry i gave it up for lent"-Brian
"Damn being a Christian -_-"-Your mom
by Coooooook March 11, 2011
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died; surrendered to death
And Jesus, having again cried with a loud voice, gave up the ghost.

King James Bible
by chevmolet March 29, 2016
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Likes nobody on any emotional level not even friendship
I honestly gave up on life 😎
by Yeeeeeetttttt April 26, 2019
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