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A term coined by esteemed Gonzo journalist Hunter S. Thompson in his memoir, Fear and Loathing in Las Vegas. As used in the context of the book, the term refers to the consumption of near-lethal amounts of hallucinogens, narcotics, stimulants, alcohol and tobacco.

The term can also be seen as part of Thompson's commentary on the perceived descent of American society into moral degeneracy and hypocritical hedonism, largely due to the misguided and greed-driven leadership of national politicians, officers of the law, and local authorities.
Fear and Loathing at Duke University.
by TheTallBoy March 16, 2009
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To Fear and Loath

Going out for a massive night containing random adventures, multiple locations and fuelled by plenty of body and substance abuse.

Reference to Fear and Loathing in Las Vegas
Iโ€™m going out to fear and loath tonight.
The guys were fear and loathing last night.
Fear and loathing finally caught up to me.
The fearandloathers site touched me the way fear and loathing would.
by Easy-E. August 30, 2006
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Whenever you consume a vast plentitude of drugs and/or alcohol. It is a reference to Fear and Loathing in Las Vegas, the work of gonzo journalism by Hunter S. Thompson (and adapted into a movie starring Johnny Depp). It is usually followed by the name of either the city you're in or whatever location the binge took place.
Dude, Alex and I did 30 reds, a tap of acid each, 6 lines, and half an ounce of pot each last night! It was fuckin fear and loathing in san francisco, man
by dr_gonzo February 01, 2006
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a weekend set aside for the exssive consumption of narcotics with total dissregard for personal saftey and the saftey of those around you.
the term can be used retrospectivley to describe the complete abscence of any memory of the weekend caused by massive brain damage from narcotical abuse.
man i have no idea what happened after i downed my first pill on friday i just woke up sunday mornin after fear and loathing.
by tony morris May 23, 2006
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Emotions felt when attending a party heavily populated with douchebags and douche-driven whores (who account for much of American female teenagers).
In a frenzy of fear and loathing, I escaped the "jumpin spot" of the party and found a secluded corner, where I chain smoked and drank someone else's rum.
by friend of bob June 15, 2004
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An action or event that is so restrictive and/or difficult that it could literally cause brain damage.
'Living in a box his entire life pushed johnny into fear and loathing'
by Warren August 26, 2003
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