Fatsuke Share definition Flag Of or relating to a lack of knowledge. Also considered a person who has a mental disability I was going to ask my friend for help with homework, but I remembered that he failed last weeks quiz, and therefore must be Fatsuke. Fatsuke by Messy and Bloody Poop October 20, 2021 0 0 Get merch Get the Fatsuke mug. Buy Now — $32.95 See more merch