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downsyndrome 

Genetic condition caused by a triple chromosome also known as chromosome 21. People with this condition are blessed with the gift of eternal innocence. They are usually harmless and friendly and incapable of violence. We like to think they need help but maybe it's really us who do.
"George Bush is a perfectly sain individual, no history of downsyndrom there, he can wage war all he wants"
downsyndrome by Flo January 29, 2004
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Downsyndrome 

An extremely intelligent person who doesn't deserve hatred. Please keep the negative comments about Down syndrome people to yourself. Thank you
My little brother has {Downsyndrome} and is very intelligent and adorable!
Downsyndrome by alay.s May 5, 2016

Debbie Downsyndrome 

A person who is always down and it a bad mood, and puts others in bad moods as well. Usually is in a bad mood from being ugly or gettin made fun of.
person 1: "Tough fish"
person 2: "Heis, stop being Debbie Downsyndrome for 5 min"

Double Downsyndrome 

When two adults with down syndrome have a kid who also has down syndrome. Jokingly the kid would have twice as many extra chromosomes.
Double DownSyndrome
Doctor: No, you two shouldn't try for kids!
Dad: Kids? Kids!!
Kid: Nnyaa!

Internet's Down Syndrome 

A temporary condition brought on by the lack of internet connectivity and characterized by irritability, fidgeting, lack of focus, a general feeling of helplessness and occasionally exercise.
Steve: What's up with the glazed look on Meredith's face?

Brad: Well, she likes to start her day reading Perez but we have no connectivity and slipped into an acute case of Internet's Down Syndrome.

chow down syndrome 

a portmanteau of the words "chow down" and "down syndrome," meaning the loss of mental acuity following a hefty meal; aka food coma.
Is he alright?

He's fine. Just a bit of chow down syndrome.

dansyndrome 

an awful disease where a man gets very hot women but they tend to be too stupid to talk to. Its very sad for the infected but it is great for the kids friends because they have someone new to jerk to
Wow daniel's girl lizzy is sexy. Shes probably stupid though, daniel has dansyndrome
dansyndrome by moviegoer1239 December 6, 2010