The world 'chromosome' is usually used to bully someone
GameGod22: Hey Burt, I didn't like how you said Hello yesterday
Burt: Idc I have more chromosomes then you

*GameGod22 goes crying**
*GameGod22 kills himself**

Burt: Well that's 1 less chromosome to handle!
by BlockBoy72 July 6, 2018
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Meaning you have an extra set of chromosomes. Nice way of calling someone a retard. Powerplay is a man-up scenario in sports, mostly from opposing team serving a penalty.
Person 1: "Wow, that guy is a moron."

Person 2: "Yeah, they must have a chromosome powerplay going on."
by M_Dubz152 June 7, 2023
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(n). One who steals another's chromosomes to bring about autism, down syndrome, etc.
Look out, there's a chromosome thief coming towards us!
by _thememeprophet_ February 27, 2017
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What makes a Down's Syndrome person how they are.
Timmy has an extra chromosome, that's why he goes to special school.
by Ray Flynn May 11, 2005
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That one kid with Down syndrome you grew up with. The one that was sometimes too violent because he didn’t know his strength, but everyone still like him because of his earthly wisdom
Watch out, Sensei chromosome might teach us some new fighting moves
by Teamumizoomi March 25, 2020
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A way to reference autism in a more satirical and humorous way.
Thomas: "Ayy man, this nigga spreadin' his google chromosomes around, what we gonna do?"
Ben: "Shut the fuck up Thomas, I'm sick of your bullshit; everyone is."
by Scrötumm Teeklurr June 11, 2017
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