The fatigue that occurs as a result of playing several competitive, high-spirited games of NBA 2K (any year applies) games consecutively. Often results in needing a long break from the game.
Jeff: Daaaaammmnn that was crazy, Kobe just dropped 42?!?! Wanna rematch?
Clyde: Nah brother, I'm all 2Ked out.
Clyde: Nah brother, I'm all 2Ked out.
by Rick da Ruler October 24, 2012
Get the 2Ked Outmug.