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The fatigue that occurs as a result of playing several competitive, high-spirited games of NBA 2K (any year applies) games consecutively. Often results in needing a long break from the game.
Jeff: Daaaaammmnn that was crazy, Kobe just dropped 42?!?! Wanna rematch?
Clyde: Nah brother, I'm all 2Ked out.
by Rick da Ruler October 20, 2012
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