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A walk down Main Street.

She had a headache, So I recommended she take a walk down Main Street.
by R37RY November 3, 2011
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Mainstream

Something that's popular. Sure, it's trendy, sure, it's probably on MTV and popular among people-but, honestly-is it really that much of an issue if I have Lady Gaga on my Ipod? She's in there with Amanda Palmer and Porcelain and the Trams as well-am I indie enough for you?

The lot of you are being really rude. Some mainstream is good, it's not the end of the world, so stop complaining that somebody else likes Rihanna and you like The Decemberists.

Grow up.
Person A: Hey, have you heard the new release from Lady Gaga? It's pretty good. I think I"ll give her a chance!

Person B: Umm..that stuff is forced down our throats by mtv and stuff. You shouldn't listen to that. Here, I got a new album based off of a Pitchfork review, you should try it.

Person A: *listens*
Yeah...no offense dude, but I don't like it.

Person B: *scoffs* You're just another one of the sheeple. A slave to the mainstream. You just have bad taste.
by Polygame January 2, 2011
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Main DRUG Source in America

U.S goverment! getting our money both ways! Back in the late 70's, early 80's when crack cocaine first started showing up, it was distributed in tiny glass viles. I'm sure someone knows exactly what I'm talking about. Anyways, why wasn't there ever a huge crack bust back when it all began? It was almost ALL in these tiny viles..meaning someone was buying a hell of a lot of them from somewhere. Why didn't the government track who was buying all these little viles and bust them? I know why. Because it was the government who was distrubuting the crack. Sure, now days people can make crack in their own kitchens. But back when it all started, I think it was the government. They did it to help pay off the Vietnam "War"
Iraq & Afganistan (drugs have become larger in this era)
by WhiteBlood June 17, 2004
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main boo

your main girl, not in a serious relationship but basically she gets the dick first but they can see other people and shit.
DeAndre: manne my main boo is out i need muh gutta bitch

Carlos: i feel ya bro
by 123fukme January 17, 2008
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maïnk

A friend who,s part of a anonymous Maïnk club
by Un Vrai Maïnk April 5, 2004
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Garen Main

A Garen main is a person who is either new to league of legends, has played league of legends and is still trash, or just a person who lives for the memes via the wet noodle slap or spin to win.
Mid: Garen... wtf are you...
Garen main: DEMACIAAAAAA! *dies*
by ForDemacia May 12, 2018
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Main Squeeze

I see John over there with Kayla, man, I need a main squeeze!
by Whitney May 11, 2003
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