This is a more inside way of saying you have to drop a deuce (take a crap), it works really well in an office setting so that you may let your close, personal co-workers know where you are going without letting everyone else know. This is derived from John Wayne's nickname being "The Duke", and can be shortened by simply saying "I have to make a phone call", or added to by saying "man John Wayne has been calling me all day."
"I'll be right back I have to make a phone call to John Wayne."

"I'll call you right back John Wayne is calling me on my other line."
by the crab show July 08, 2009
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drop off John Wayne

Verb: A term used to describe a difficult bowel movement. A play on word based on his nickname, "The Duke."
We might be late to the movie. I need to drop off John Wayne.
by J. Lightning August 27, 2010
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Wayne John

WAYNE JOHN! WAYNE JOHN! WAYNE JOHN! HE STOLE PENCILS! FROM ME.
by Fatcockdisorder69 June 01, 2020
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ay man i gotta go my girl want me to come over and i aint got nothin. so ima go buy me a box of dem thangs that killed john wayne
by shay shay baby April 12, 2008
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John Wayne

A black coffee. No sugar. Especially in jails and prisons of NJ
Ay bro what you drinkin?? Oh this?? A John Wayne.
by Ricky Shroomz March 12, 2021
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John Wayne Camp

Dang i just took her to John Wayne Camp and made the nasty.
by Schweaty Balls March 02, 2011
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