isolation

In poker, a technique in which a player reraises a weaker player's bet, trying to play him heads-up (one on one) by making it expensive for any other players to call.

Bruce Lee: LaVar Arrington used isolation on Warren Sapp and forced Urlacher, Shaq and Busta Rhymes to fold.
Jose Contreras: LaVar is a fucking monster at poker, I'd never sit down with him.

by benny b from the bronx February 22, 2005

Isolation

To be alone and nobody is around

What Jack Pulinko feels is full on isolation

by JackHesmelllinkos October 17, 2019

methionylthreonylthreonylglutaminylarginyl...isole

A big ass word that mr. Beast read for over seventeen hours in a video.

Bab: Pneumonoultramicroscopicsilicovocanoconiosis is the biggest word
Beb: No, methionylthreonylthreonylglutaminylarginyl...isole is the biggest word!
Bab, Bib, Bob and Bub: IT'S ALMOST BEEN A FULL DAY, GO THE FUCK TO SLEEP

by AARIES. September 2, 2020

Italian Isolationist

Nickname given to Kobe Bryant by Colin Cowherd of Sports Nation.

The Italian Isolationist could easily take the Akron Hammer in a game of 1-on-1

by CrunchyDeluxe November 10, 2009

Methionylthreonylthreonylglutaminylarginyl...isoleucine

A shortened version of the longest english word. The actual word has about 900,000 characters (189,819 to be specific). It is the chemical name for titin, which is the largest known protein. The word is obviously rarely used as it takes about 3 hours to pronounce, and it would be a lot quicker to just say "titin".

If you want some big protein, might want to look for something with a lot of Methionylthreonylthreonylglutaminylarginyl...isoleucine

by ExplosiveKrypton January 6, 2017

ISFLY

I still fucking love you.

Damn, isfly. :(

by silvermiee:) June 16, 2009

IPoly

A Complete motherfucking shit hole, where happiness, strong work-ethic, and meaningful relationships go to die. It's the Ghetto before the Concentration Camp. While you are struggling to communicate with your team members 30 minutes before a project is due, dirty homosexuals are kissing and fucking on tables and under a shade every day. Meanwhile, the "Cool Kids" are doing Wax Pens in the bathrooms, and your best friends are writing essays about what a "shitty person" you are. Not to mention couples are breaking up every day and then getting back together in the seconds after.

Person 1: Hey man how is your life going?

Person 2: Sorry, I go to ipoly my life does not "go".

by AbelDaalman April 9, 2019