Cranial-Rectal Entanglement Syndrome (also known as Anal-Cranial Entanglement Syndrome, or ACES) is a disorder which is characterized by someone who is incapable of performing a simple task due to pure stupidity or an apparent misplacement and, therefore, disuse of their cerebellum and cerebrum.

Esp. applies when someone has one job and cannot complete it properly, if at all.
Karen suffers from such a severe case of Cranial-Rectal Entanglement Syndrome, she has a visible tan-line around her neck.

I’ve run into a catch-22 due to two of the people I rely on having ACES.
by Dominus Pollux February 06, 2019
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corporate-speak or PC phrase to describe someone who's got their head stuck squarely up their ass.
Not sure what's going on with Joe today - he's acting like a real jerk. Maybe he's suffering from cranial rectal proximity syndrome
by Annakaleia September 30, 2011
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Main symptom of advanced stage of LPOD.
Characterized by increasing inability to form coherent thoughts or communicate effectively, resulting in uncontrolable urge to attack conservatives with mobian logic, pies, and condiments.
DNC, House & Senate Democrat roster, Klintonistas.....
by Milo Mindbender May 06, 2005
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cranial bypass

Having too much to drink too many times, or otherwise strained the brain, so that a person doesn't remember something that happened or that was agreed to before. Can be a result of Cerebral Bulimia.
I know I told you that I'd never screw around at college," said Luther, "but that was before I had a cranial bypass at my freshman dorm.
by LA AC September 28, 2010
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A condition wherein the patient's rectum is blocked (impacted) by their own cranial matter, resulting in the following symptoms: inability to think critically, difficulty processing rational arguments, loss of desire to collaborate. Oddly it does not impact the ability to pass flatus.

Those suffering from this condition also often suffer from procto-milontas.
Nurse - the patient is clearly suffering from a cranial-rectal impaction (syndrome). Please provide 30 mg of Thorazine and be prepared to perform an attitute adjustment.
by Patrol Jeff May 11, 2023
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Cranial

Cool, Crazy, What’s “In”, or What The Cool Kids Are Doing
by KatBizzle November 19, 2023
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Cranial

Crazy; Cool; What’s “In”; What The Cool Kids Are Doing.
Man, that party last night was so cranial!
by KatBizzle November 19, 2023
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