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Ur sisters a mister

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Even worse than ur mom gay, ur dad lesbian and ur granny tranny! Makes Jupiter explode!
Pete: Ur granny tranny
Alex: Ur sisters a mister
Jupiter *explodes*
by JrgnVS March 14, 2018
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Worse than “ur granny tranny” or “ur brothers a mother”. Every time this is said, the victim will implode into a ball of guts then blast into a shower of blood.
Joe: “Your gay.”
John: “Don’t make me do it.”
Joe: “Do what, pussy?”
John: “You’ve taken it too far.”
John: “Your sisters a mister.”
Joe: *Implodes then blasts out covering the walls in a red layer of blood and guts*
by ThatGuy286437 May 15, 2018
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The girl rule that your friends are always more important than your boyfriends. Basically the girl version of bros before hoes, except the title doesn't sound like an insult to women. Also, there's an unwritten sub-rule: if you catch your friend's boyfriend cheating, YOU MUST TELL HER ASAP!

Sometimes called chicks before dicks.
Amy's boyfriend was being such a jerk to her BFF, so she dumped him, even though she still really liked him. What an awesome friend Amy is, putting sisters before misters like that!
by Disvan November 26, 2010
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Dr.sisterfister

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The man, the pope, the doc, the absolute gamer, a madlad thats has 3 monitors and a bunch of stash of anime girls, what a guy, yeah, oh but I have to warn you that he sometimes will ra-

and someone ship him with audiction, idk who, and idk when but...yes its real
Person 1: do you remember his name?, that youtuber I saw earlier in the streets?

Person 2: oh, the one that carries 2 anime body pillow?

Person 1: yea

Person 2: his name is Dr.sisterfister

Person 1: oh thanks
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The unwritten law that dictates that a the wishes of an unmarried woman's or girl's female friends trump those of a men she wants to have a relationship with. This law exists to protect said woman from being roosterpecked or whipped and her boyfriend's a pig or a man slut.
Better known as ladies first and to hell with your boyfriend.
Yo, lady, don't let that male chauvanist pig tell you what to do. He thinks you're just another piece of ass. After all, it's sisters before misters.
by Stop the Pendulum April 14, 2006
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sisterfister

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Strictly, one who indulges in a particular form of incest, using only their hand (see fister. Often used as a term of contempt, and shortened to "sissy" on account of their unadventurousness.

See also brotherfucker.
Your brother's such a sisterfister, you know.
by Lucifer B September 20, 2005
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Sisterfister

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Adjective meaning an alternative, clean version to Mother Fucker
*joey smacking Sarah on the butt
Sarah - "Ouch you sisterfister"
by Hink68PMMF October 25, 2017
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