It is originated from chinglish "zhe bu ke xue". It is always used to express surprise or astonishment at unexpected or unusual things. By saying that, one means the thing he/she is told or sees is out of his/her expectation.
A: You know what, Tom just got the offer from Morgan Stanley, but he rejected it and decided to go to a small local bank.

B: Oh, that is not science.
by ritotila April 27, 2014
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An Electro Respiratory Ballistic Optimization smoking device, or an ERBO.
"We smoked from The Science!"

"Man, The Science fucked me up."
by Chris M. Flett February 18, 2008
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teacher: can someone name me a prime number
idiot: err...21?
teacher: no, you fool, 21 is a product of 7 and 3
student: you've been scienced
by Emily O November 27, 2007
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The event in which, while gaming, something unexpected happens and you need to explain why.

Alternatively it is used to explain why you are doing something difficult or boring but provides rewards on completion.

Finally it can be used as a good old exclamation in everyday life.
Example 1)

*Character is floating in mid-air*
Observer: What!? How is that possible!?
Gamer: SCIENCE!

Example 2)

Observer: Why are you going all the way over there for a sword?!
Gamer: because SCIENCE!

Example 3)
Person: SCIENCE!
by Jigsaw232 August 31, 2011
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SCIENCE! can be: I(f) = ((2hf^3)/(c^2))(1/(((hf)/(e^kT))-1))
by Kiousu July 6, 2009
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Of or having to do with science. Can be used as a short form of scientifically
Earth being round has been proven sciencely.
by dgwe September 2, 2016
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Science is a subject that not everybody likes In primary school people can't wait to go into secondary school and use every chemical invented in on this planet earth.But when they get to that stage they end up writing and doing so much equations ending.
MOM:WHAT DID YOU DO IN SCIENCE

TODAY .
ME:I DID EQUATIONS
MOM:SCIENCE NOT MATH
ME:YEAH EQUATIONS
by VictoriaCrown1 February 25, 2018
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