When a member of a band, particularly a vocalist or frontman has the tendency to leave and join bands several times. Sort of like a disease.
Chris Cornell left Soundgarden for a solo career, then joined Audioslave, left them for another solo career.
once the infection starts, it's hard to stop, and you'll be left to aimlessly join bands, and leave intermittently for no apparent reason.
Bassist: Dude our singer just quit!
Drummer: Man, what do we do now?
Guitarist: Screw him, he's got Chris Cornell Syndrome, he's been in like 50 bands.
Bassist and Drummer: Gross, who does that?
once the infection starts, it's hard to stop, and you'll be left to aimlessly join bands, and leave intermittently for no apparent reason.
Bassist: Dude our singer just quit!
Drummer: Man, what do we do now?
Guitarist: Screw him, he's got Chris Cornell Syndrome, he's been in like 50 bands.
Bassist and Drummer: Gross, who does that?
by Lordofpoo May 14, 2011
Get the Chris Cornell Syndromemug. The worst, dirtiest college hockey team ever, relying only on big dirty hits and injuring opponents. The only reason they can ever win games is when they injure all the players on the other team. No other team plays like football players or boxers like they do. They have no skill at all and it shows.
by Hokee February 17, 2023
Get the Cornellmug. by itsyagurlsofii February 16, 2019
Get the Cornelmug. by Lexi is bae March 14, 2023
Get the Lexi Lola cornell whitemug. by Liambaka April 13, 2025
Get the Cornell Shakermug. 
by TOW DOWN!!!!!!!!!!!!! July 30, 2024
Get the Cornel Westmug.