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Iocaine powder

(Fictional). A powerfully deadly & undetectable poison originating from Australia. Both colourless and odourless (in Australia, the correct spelling of those words), iocaine powder will dissolve instantly when poured into a liquid. However, starting with a tiny dose and carefully increasing consumption over time, one can build up a tolerance to iocaine.

The substance was introduced in "The Princess Bride" (1973), a novel by William Goldman, where it featured in a battle of wits between the Sicilian criminal genius, Vizzini, and the mysterious Man in Black. The scene was later depicted in the movie "The Princess Bride" (1987). References to Iocaine powder have subsequently been made in movies "The Haunted Mansion" (2003) and "Jack and the Beanstalk" (2009). In the latter, it's mentioned by the pawnbroker played by actor Wallace Shawn, who starred as Vizzini in "The Princess Bride".

Iocaine is sometimes misspelt as "iocane". The correct spelling is modelled after that of the real drug cocaine (from "coca" (the plant which produces the drug) + the chemical suffix "-ine"). It would appear that the pronunciation of the name of this poison, "I owe Cain", is a subtle reference to Cain, the first murderer (Genesis 4:8) —although it should be noted that Cain killed with some kind of physical violence, not with poison.
Buttercup: “And to think, all that time it was your cup that was poisoned!”
The Man in Black : “They were both poisoned. I've spent the last few years of my life building up an immunity to iocaine powder.”
by The Florinese Falkon April 29, 2022
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Powder

Pertaining to fetinaul, in rawest form, usually white chunks, kinda looks like crack, super expensive, people overdose on the shit all the time, waaaay better than smoking lame ass "blues" that do nothing for you once you start smoking fetty.
User- do you have/or can you get any powder ?
Connect- yea I got that fire powder, but it's 100 bucks a gram my dude.
User-so long as it's good then im down.
by HandleYourBitchassScandal666 August 14, 2025
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powder that makes you say yes

A powder that indeed does make you say yes. It derives from a recent meme.
"Have you seen the movie Yes Man? It's about a man who challenges himself to eat powder that makes you say yes"
by skunklovers December 8, 2018
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Clam powder

You should have seen the clam powder puffs as I was ass banging your granny last night!
by *******JOHN******* July 28, 2020
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Hex Powder

Hex Powder is acid salted Propylhexedrine freebase, Propylhexedrine HCl salt, or Propylhexedrine HCl.
Tony: I tried 218mg of Propylhexedrine HCl powder in water solution and then cleaned the house. That was good Hex Powder.
by GreenHexagon October 10, 2024
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Powder Punch

(verb) To blow cigarette or marijuana smoke into the anus or vagina of another and to then penetrate them.
I saw Jose sucking pipes with Consuela behind the taco van when he waved at me, bent her over and powder punched the bitch!
by Thezzar Mazzar February 2, 2010
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On a powder keg

Oblivious to upcoming disaster. Waiting around seemingly unaware that nothing can go right where you are now.
“You may not think it at the time, but you’d be sitting on a powder keg if you drove home any way but sober.”
by rabiescat November 25, 2023
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