by MrPibbEnjoyer March 7, 2022
Get the Leanmug. The term "lean mass hyper-responder" was coined by software engineer David Feldman on July 3, 2017 while posting in his low-carb diet blog: "Cholesterol Code." The blog post called "Are you a Lean Mass Hyper-responder?" quickly circulated through the low-carb community.
As background, the original term "hyper-responder" was already used by dietary professionals for years prior to Feldman's blog post. And in dietary literature, a "hyper-responder" is someone who adopts a low-carb diet, then experiences dramatic cholesterol elevation. So when Feldman wrote his 2017 blog article, he co-opted "hyper-responder," and crafted his new term "lean mass hyper-responder" to describe what he believes is a metabolically unique sub-set of all hyper-responders. Specifically, some hyper-responders begin a low-carb diet while already in possession of a very lean body mass. And yet in spite of this, they still --quite counter-intuitively-- respond with extreme cholesterol elevation. Additionally, these subjects experience a marked decrease in triglycerides, while exhibiting excellent metabolic health. The entire phenomenon defied a long-standing metabolic theory called "The Lipid Energy Model," presenting a scientific conundrum for Feldman.
Feldman believed that all this was a significant observation worth exploring. And his efforts eventually led to a 2023 research project called "The Lean Mass Hyper-Responder Study" led by Dr. Matthew Budoff and Dr. Nicholas Norwitz at Lundquist, UCLA.
As background, the original term "hyper-responder" was already used by dietary professionals for years prior to Feldman's blog post. And in dietary literature, a "hyper-responder" is someone who adopts a low-carb diet, then experiences dramatic cholesterol elevation. So when Feldman wrote his 2017 blog article, he co-opted "hyper-responder," and crafted his new term "lean mass hyper-responder" to describe what he believes is a metabolically unique sub-set of all hyper-responders. Specifically, some hyper-responders begin a low-carb diet while already in possession of a very lean body mass. And yet in spite of this, they still --quite counter-intuitively-- respond with extreme cholesterol elevation. Additionally, these subjects experience a marked decrease in triglycerides, while exhibiting excellent metabolic health. The entire phenomenon defied a long-standing metabolic theory called "The Lipid Energy Model," presenting a scientific conundrum for Feldman.
Feldman believed that all this was a significant observation worth exploring. And his efforts eventually led to a 2023 research project called "The Lean Mass Hyper-Responder Study" led by Dr. Matthew Budoff and Dr. Nicholas Norwitz at Lundquist, UCLA.
IN A SENTENCE: "Steve has always been a tall, skinny, beanpole of a guy. And then when he went on the carnivore diet, he was still skinny, but his cholesterol went through the roof. His doc said that overall he's pretty healthy, so he might just be a lean mass hyper-responder."
by Innocent Byproduct December 13, 2023
Get the Lean Mass Hyper-Respondermug. A drug created for recreational, originating in Houston, Texas. Made with promethazine
and codeine cough syrup, sprite and jolly ranchers. Without the first 3 ingredients, it isn't authentic lean. Can have negative side effects in large amounts.
and codeine cough syrup, sprite and jolly ranchers. Without the first 3 ingredients, it isn't authentic lean. Can have negative side effects in large amounts.
by shattered_dreamz January 23, 2023
Get the Leanmug. by DJFactAnomics April 24, 2023
Get the Squirrel Leanmug. The man lean consists of placing both arms (one on top of the other) on a balcony railing, and adopting a facial expression akin to that of one getting lost in fond memories of the past, while silently weighing up the pros and cons of waiting for one's partner to finally finish their shopping against vaulting the balcony and ending their suffering. Most commonly occurs in shopping centres/malls, and is similar in many ways to the man chair, although takes place outside of the store. A true form of silent struggle. Next time you see a man lean in progress, why not slip a brother a thumbs up, to let him know that things are going to be okay.
"Yo, dude, check it out, you see that right there? Man lean."
"Woah, he looks so...lost..."
"Poor guy, he's been leaning for well over half an hour, I don't think he's gonna last much longer."
"Inconsiderate bitches. Let's go talk to him."
"Hey, chin up, brother. You're fighting the good fight."
"Thanks, guys. I-I really needed that."
"Woah, he looks so...lost..."
"Poor guy, he's been leaning for well over half an hour, I don't think he's gonna last much longer."
"Inconsiderate bitches. Let's go talk to him."
"Hey, chin up, brother. You're fighting the good fight."
"Thanks, guys. I-I really needed that."
by RedderMist May 19, 2014
Get the man leanmug. I'm pretty sure lean is the standard cherry codeine and soda{ and quite possibly jolly ranchers}. I'm no certain why people bring syzzurip/syzzurip into this. Syzzurip/Syzzurip is grape promethezine and quite possibly soda. Why would syzzurip/syzzurip be, also, known as lean? Unless, if I'm mistaken. !!!^_^!!! !!!-_-!!!
"Hey did you hear about Jadar Payend!?!?!?" "Yeah, I heard 5-O{h} busted that nigga drivin' while he was sippin' on lean!!" !!!^_^!!! !!!-_-!!!
by *Hung*{ACambodianhorse-breeder March 10, 2023
Get the Leanmug. by myzolol February 23, 2022
Get the leanmug.