Spiking is done by a male or female giving a female oral sex. The giver will stand up and swat the breasts of the female receiving, typically followed by a "UGHHHh!!" or other yell of victory.
Britney: My boobs are so sore!
Ashley: Why?
Britney: Lewis was giving me oral last night when he just stood up and slapped my chest.. he was all "THE DAY IS MINE!" or something.
Ashley: You got spiked..
Britney: What?
A more mature way of saying a very well composed piece of feces. Aka shit.
Person A: Yo what the fuck dude, did you spike in my pillow case.
Person B: Me no man, thats fucked up. I think I saw Billy in there with a knife and toilet paper last night.
Person A: Fuck that, im Spiking on his goddam floor