"The Opie (real name Gregg) and Anthony Show" are consistent, quality morning commute-time-slot radio personalities. The duo (with "glorified intern", the hysterical Jimmy Norton present almost every day) are syndicated in the weekday mornings from 6-9, and then on uncensored satellite radio from 9-11(AM).

A typical show can include story bits (radio bits that evolve from a witty or shocking story by anyone in the studio), celebrity call ins, an appearance by one of many of the shows' "unique characters" (ex. a 50 some odd woman, who is homeless and a virgin) or all of the above. Not greatly structured (but by no means "amateur" or loose feeling), the show is non linear and follows little pattern, with Op generally keeping the pace unfolding with new topics, while Anthony (and Jimmy) keep it loose.

The show is heavily criticized by fans of Howard Stern ("Howie" as he is commonly known in studio) as well as Howard himself, because he feels the radio duo has taken a formula he created and perfected, and he is (or seems at least) greatly disrespected by it. The two radio shows have been feuding ever since.

For the skeptics, give the show a chance.
"The Opie and Anthony Show" is a constantly evolving, uproariously hilarious talk show that usually does not get the respect it deserves.

FRRUUUUUUUUNKISSSS!
by deadface October 1, 2007
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A band so old and unpopular it's almost unheard of.

Leader of the band: Jonathan McClure (now a geography teacher) along with some of his friends played really bad covers in the attempt of becoming famous
Erika: Have you heard of the band "Opie Goes to Kansas?
Baleigh: No...but they sound lame
by MinecraftAddict_ November 26, 2016
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An exclamation one uses when a major catastrophe occurs. Comes from the sign a woman was holding that was struck by a 2021 Tour de France rider, causing almost the entire peloton to crash in a massive pile-up. Literally means "Go grandpa-grandma".
*gigantic asteroid crashes into the Yucatan Peninsula 65 million years ago*
T-Rex: "Allez opi-omi! That doesn't seem so good."
by Nicholas D July 29, 2021
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Slang term for being high on or feeling "doped out" on any type of opiate drug.
Those opiate drugs ills will make you feel opie dopey.
by Cmart420 March 15, 2017
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Slang term for being high on or feeling "doped out" on any type of opiate drug.
Those pills will make you feel opie dopey.
by Cmart420 March 15, 2017
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When something is OP. For example, Blitz-War, his subscribers, motorized decks, or Rover Wombats.
These jeeps are some opie shit, man
by Billy41 May 20, 2022
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A cat featured on the Youtube channel Moriah Elizabeth or the old name Genuinely Moriah.
Moriah: Hi Opie!
Opie: Hi.
by AthenaPlayz September 19, 2020
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