duff

designated, ugly, fat friend

That fat bitch over there, with those other girls, is so ugly... she is such a duff.

by Liz O'nya August 15, 2016

Duff

DUFF - Designated Ugly Fat Friend.

Doesnt have to be fat or ugly. The weak link in the group of girls. The least attractive but it the most approachable. Use her to speak to the girl in group you want to score with.

"Damn Cindy so hot, how do i even get a chance to speak to her?"

" its simple my friend, get to know her DUFF Sarah & youre in"

by Jamattack July 17, 2016

duff

D.U.F.F a friend that is used to make yourself appear attractive or popular

wow really their friendship group has a duff wow they are so shallow poor duff

by TechWhiz November 2, 2016

Duff

A blonde chicks vagina.

"Hillary's duff"
"Go get you some of that duff over there"
"I bet that chick has a nice duff"

by Fagboyslim88 January 13, 2017

duff bag

A monster tard you work with. Usually nothing good comes out of there mouth. Comparable to douchebag

Duff bag just moves around the office soundung drunk

by Going6to6hell6 January 19, 2017

duff

The stuff left on the bottom of your weed bags. All the stems, crystals, and leafs. Often used as a cheaper alternative to buds in baking. Though often mistaken as good, and used in joints and bowls. Known to be sold for as cheap as 30-40 dollars an ounce.

Hey bro, got any of that duff? I need to make another's batch of weed brownies.

by fitzy_keegs January 13, 2017

Duff

dumb ugly or fat friend...

Becky invited her duff so she doesnt get wasted and blows any willing cock within sucking distance

by NorCal Slanger March 27, 2017