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duff

Madi and lily (designated, ugly, fat friend)
Madi and Lily are such duffs!
by YLYILS May 26, 2018
mugGet the duffmug.

Mickey duff

Mickey Duff was a well known boxing promoter whose name is now universally used as rhyming slang for marijuana.

Mickey Duff = Puff
If you want me to roll one up you’ll have to pass me my Mickey Duff.
by Loftier January 23, 2021
mugGet the Mickey duffmug.

DUFF

It means "Designated Ugly Fat Friend". They don't have to be any of those, but that doesn't mean they don't have friends more attractive than them. The DUFF is basically the least attractive one in the group.
"She's cute, but her friends are hotter. She must be the DUFF."

"He's the youngest in the team and acts as the Gatekeeper to the rest of the team. He's a DUFF."

"That teacher is being left out from other conversations... He's a teacher DUFF."
by WattpadBlogger September 21, 2017
mugGet the DUFFmug.

DUFF

A term describing depressed, ugly, feminist females. DUFF for short.
"An ugly chick i know complained that i wasn't open minded enough about her genderless kitten, and that i was being sexist, and was also guilty of raping her."

"Oh she must be part of DUFF."
by mahaaham May 30, 2015
mugGet the DUFFmug.

duff

as in to bone a chick. to get duffed out
i duffed this sweet dude last nite yeahhh!!!
by gap slammer November 7, 2006
mugGet the duffmug.

Duff

V. To plan a sexual encounter and back out soon after, to stand up.
He said he wanted to be with me, but then he duffed out and changed his mind.
by Laurie-Bell February 1, 2009
mugGet the Duffmug.

DUFF

Jim: Bob you are my designated ugly fat friend (DUFF)
Bob: I'm not that fat!
by z108108 February 18, 2015
mugGet the DUFFmug.

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