Sis

A word used to replace argh when seeing or hearing something disgusting. It can also be used when someone is acting like a bitch or a slut.

Person A: Cow manure is edible and nutritious in India.
Person B: Sis, that's disgusting.

Person A: I had sex with 5 dudes today.
Person B: Sis!

by Thedarklol October 15, 2021

Sis

Word used by bitchy Twitter Stans in a usually rude context, who think that they are top shit. These Stans are usually female, and tend to overuse words such as Tea and Y’all.

Twitter Stan: Sis..
Me: You know, I’m just about done with your shit, “JunkookFangirl97”.

by MeganTheCreator April 02, 2019

sis

the girl version of “bro”, used as a form of address.

A (girl): wassup bro
B (boy): wassup sis

by FlamePh November 07, 2023

sis

used if mad at someone or you are spilling tea

“hey rebecca, i just beat you in gamepigeon.”
“SIS”

“sis i have tea ☕️”
“SIS SPILL”

by November 29, 2018

sis

a stinky poo

I am so sis
Wait you're a stinky poo?

by oiasdhyf dss December 02, 2023

sis

sis meaning slave in suffering

your a sis aren’t you

by dwntwrry December 20, 2021

Sis

Sis is the noun for describing a queen who is in shock.

Ciara: Omg i met Sammy last night

Ben: OMG sis

by Ciaranadben October 14, 2021