An expression used primarily in the southern U.S. to tell someone who is acting impatiently to calm down.
Person #1: Ya'll best be fixin' to get them fences up 'fore I get mind to tan your hide!
Person #2: I reckon you keep your panties on, darlin', or you gon' get madder than a wet hen!
Person #2: I reckon you keep your panties on, darlin', or you gon' get madder than a wet hen!
by RebelLass84 August 28, 2015
Get the keep your panties onmug. Keep Yourself Safe typically means "kill yourself", as both words have the acronym KYS. Very useful for filtered chats as you can wish death upon someone without moderation being up your ass.
by BigBouncyKittys October 12, 2022
Get the Keep Yourself Safemug. 
Get the Keeping it freshmug. A phrase used by Austinites, (especially of the college-aged demographic) that reminds us not to allow huge companies to take over the unique town of Austin, Texas.
by ian the d March 25, 2004
Get the keep austin weirdmug. by >[b0bBy D]< April 24, 2008
Get the keep it a hunnit(hundred)mug. What to say to someone when they're getting too excited about something (can be anything).
Another way of saying "Calm down!".
Another way of saying "Calm down!".
by El_Barto October 20, 2004
Get the keep your pants onmug. by Cooper K October 14, 2020
Get the Keep the hoes on their toesmug.