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Oof is actually the dying sound in the game ROBLOX. Often a meme associated with embarassment, stress, worry, saddness, injury, or just not knowing what else to say. Lots of people are misguided that it is a sexual noise, but it is not, just a sound from a game.
Oof the teacher called on me and I got the answer wrong.

"Oh, yeah my kid bumped his knee on the table today."
"Oof."
"I know."

Oof my homework is due.
Oof by a_Roleplayer May 24, 2018
Related Words
oof oofer oofer gang Oofing ooft oofa! oofed Oofles oofy Oofie
The sound a roblox player does when it dies or resets. Also known as an exclamation like "Lol" or "xD"
-"Lol I have to go to clean up an injury xD" -" Oof ok xD"
Oof by Wolfning April 15, 2018
Oof is defined as the new Roblox Orgasm since it's filled with adult content.
Thottie666: Ooof
Oof by xx_thotslayer_xx April 16, 2018
a cry for help
*nigga fucking dies*

*Some Goofy Nigga: OOF
oof by Qvshout May 28, 2018
what is said when you realize you just made a women are property in a feminist group
man: hippity hoppity women are property
every single female around him: EXCUSE ME?!
man: oof
oof by TheBurningBox May 29, 2018
When a guy from roblox is devoured by the ultimate unavoidable death. Happens to everyone who plays.
Player 1: i'ma keel yu now!!!!!!!!!!!!!!!!
Player 2: Oof!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Oof by dope derp May 29, 2018