What's up guy?

simply put: the best combination of a three word greeting ever

Girl: Hi
Guy: What's up guy?
Girl: Oh my god! (orgasm) Take me now

by Gtag4 October 23, 2005

what's up people?

The song title of the 2nd intro to the anime series "Death Note". Song is written by Maximum the Hormone. The song is a metal song and song in Japanese.

"Dude, this intro is WAY better than the first! I'm glad they chose "What's up people?" to play in the intro now."

by Justin Ellsworth August 29, 2007

what's up

Possibly derived from "what's the update." Extremely overused, almost exclusively by America's youth.
Sometimes I wonder why people always ask each other the same question over and over again, when answer is always "nothing." Are we really that dull?

Mike: What's up?
Matthew: Nothing. If you ask me again I'll roast you.

by Renaissance Woman 4 u January 8, 2005

That's What's Up

A way of agreeing to what the other is saying. Or if they ask you a question it can also mean that you are down to do what they're asking.

1:"Ay mayne, i got this killa, we blazinituptoday?"
2:"Shiiiit, that's what's up!"

by MonalisaelisaDelafusa April 8, 2009

G's up, Ho's down

Bangin ass ecstasy pills
popular in jersey

u got sum G's up, Ho's down ma nigga?

by munx March 30, 2007

what's up man

the proper way to ask a man/woman what is happening in their life at the moment

what's up man? I heard you got the clap.

by tsssisssisss April 20, 2013

What's up?

There are many definitions for this.

1. The opposite of down.
2. The sky
3. The clouds
4. The sun

5. Space

If you want to be boring, you can just say:

1. Good
2. Bad
3. Okay

Me: Hi

Mom: What's up?

Me: The opposite of down.

by OofBanana March 19, 2019