A variation of the the Shiznit, to mean something is the goddam best of the best, when shiznit just wont do.
ie:
Mik: I met this great girl, she is the shiznit, no wait, she is the ultimate shizzle with the nizzle!
Mik: I met this great girl, she is the shiznit, no wait, she is the ultimate shizzle with the nizzle!
by Lucy-doots October 16, 2003
Get the shizzle nizzlemug. 
a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastdardization of "I concur with you whole heartedly my African american brother."
"fo shizzle ma nizzle that is dank shit"
by yo mama's snatch March 15, 2003
Get the fo shizzle ma nizzlemug. "fo shizzle ma nizzle" is a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastdardization of "I concur with you whole heartedly my African american brother"
by Anonymous November 10, 2002
Get the fo' shizzle my nizzlemug. "fo shizzle ma nizzle" is a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastdardization of "I concur with you whole heartedly my African American brother"
by John June 23, 2004
Get the fo shizzle mah nizzlemug. recently been in the news...something to do with some courtcase
by whatever July 25, 2003
Get the Shizzle my nizzlemug.