Lose The Knees 

Being way beyond the stage of intoxicated, to the point in which you begin to stagger and fall. Hereby losing the knees and the ability to walk.

If he continues to drink vodka, he is gonna Lose The Knees.

I was so shmammered last night that I lost the knees when trying to walk home.

Lose The Knees by Shmuckered October 11, 2010

Lose Off Booze Off 

A drinking game that plays as follows:
3 players and up

-A 2 player game is selected (ex. NHL, Madden, Mortal Kombat)
-The game is played
-Losers drinks the amount of points/touchdowns/etc. they've lost by (ex. 5-3 loss, drink 2 shots)
-The controller stays with the winner, the loser passes the controller
-Tournament finals may double the ante - 2 shots per lost point.

Guaranteed to get you hammered and you'll even have fun doing it.

Ages 3 and up.

"You think you're better at NHL than me? It's time for a Lose Off Booze Off"

"I was gonna come to church today, but I had a Lose Off Booze Off last night."

"How did I wind up in the hospital? I lost 11-2 in the Lose Off Booze Off finals."

Lose Off Booze Off by bodiddles March 31, 2015

Lose Your Dnim 

The title for Teen Wolf: Season 3b. It sums up what happened to one of the main characters: Stiles Stilinski. He becomes possessed by an evil Japanese spirit known as the Nogitsune, or Void Kitsune, and goes insane- becoming trapped in his own mind. His body, under the control of the Nogitsune, goes on a homicidal rampage with the Oni, (ancient shadow samurai), feeding on pain and destruction- of which the Nogitsune gets pleasure from.

Jeff: Get ready for Season 6! The last Season! You might just...Lose Your Dnim...
Me: Damnit Jeff.

Lose Your Dnim by Void_Ludwig September 3, 2016

lose your lunch

The act of vomiting. See ralph chunks

Dusan, stop drinking. You look like you're about ready to lose your lunch.

lose your lunch by Wiseman June 27, 2006

Lose the Bet 

Slang term for jacking off. Comes from the bet featured on Seinfeld.

"Hey man did you lose the bet last night after your girlfriend left?"
"Yeah dude, we're stuck on second so I had to do it by myself."

Lose the Bet by Prettyflyforawiteguy January 12, 2010

lose your head 

lose self-control; panic.
synonyms: lose control, lose one's composure

Don't lose your head over John. He isn't worth it. I'm sorry. I got upset and lost my head.(the free dictionary)

lose your head by marina😎 January 24, 2017

lose your manners 

to fart or pass gas or to expel gas from your buttocks

Ooo Mr. Saint, you need to stop in the hall to lose your manners! This room stanks.

lose your manners by Sanja, Katie and Grant November 1, 2007