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Refers to sacrificing ones self for a friend by taking up company with the ugly friend. Can usually be captured using an iphone application such as iGrenaded. It refers to a solider jumping on a live grenade to save others.
Your friend meets a hot chick hanging out with her not so attractive friend. In order for your friend to hook up you have to hook up with her friend or jump on the grenade.
Grenade by Professional Wingman January 18, 2010
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Jersey Shore Term. The ugly friend that tags along with a smokin' hot chick. In a way she explodes and that affects the friend she's with so she's also a cock block. Really ruins the mood. Makes you feel like you're being closely observed by a gay friend. She can also be the wing-girl. Just in case there's a double-team comin' along.
My friend ended up gettin with a hot chick, while I was stuck with the Grenade.
Grenade by Hakrim August 1, 2010
ugly/fat chick out of the group of chicks.
Situation: Looks like we got a situation here.
Pauly D: Yeah we do
Situation: Alright heres the plan, we extract the grenade from that room, put her in a separate room for her to explode (sleep).

Pauly D: Alright then?
Situation: Then we extract the hotties n take em to our room. Sounds like a plan?
Pauly D: Yeah lets do it, GFA!.
Grenade by ThatGrenadeSituation September 19, 2010
You: WHAT ARE YOU ASKING FOR, BRUNO?!

Bruno: To give me all your love is all I ever asked... cause what you don't understand is I'd catch a grenade for you!!!
grenade by sad88 September 8, 2011
A grenade is what the fat ugly bitch that is with a group of fine ass women is called. If she gets upset then it "blows up" the time for the rest of the girls in the group or the guys trying to get with them.
Dude go lay on that Grenade for us she is about to get pissy and its gonna fuck it up for all of us!
Grenade by Greatest EVR August 18, 2010
female

1. fat
2. ugly as fuck

looks as it she was playing a game of hot potato with a grenade and lost
guy 1: i'm drunk as shit...how's that girl look?
guy 2: you mean the grenade?
guy 1: eh fuck it i don't even care
grenade by b_sallz October 21, 2010
A grenade is a fat, ugly chick. This term was believed to be first released on "Jersey Shore", when Mike "The Situation" referred to the best friend of a girl he brought home as a "grenade".
Mike: Dude, I feel bad for Pauly D right now... he needs to entertain the grenade!
Grenade by JerseyShoreLover August 10, 2010