a krunck non-sleepin,but hell yea be eatin who likes to twist tha pizzy fa shizzy my nizzy. Tha fool cleans betta than Mr. Clean. Ya got a new best friend cause they speak nothin but tha truth in tha end. Maybe bad and u may get sad, but while ur tweekin u aint nothing but glad. And you see them still seekin....and thats the definition of tweekin.
by Queen Tweeker January 25, 2004
a tweeker is someone acting like a retard. constantly flipping out over stupid shit. just plain fucking annoying.
The lady that works at the register was being a tweeker because the credit card was too close to the register.
by used4life August 08, 2005
by Tims mom March 28, 2004
Abbreviation for "two weeker", used to describe a person who does something or goes somewhere for two weeks. Sometimes spelled "tw'eeker" or "tw'weeker"
by Wolfdog August 31, 2007
by Gary A April 16, 2004
exciting, cheap deals that are better than ebay provided by your neighborhood crankster which he probably stole so he can buy more drugs at dirt cheap prices.
Hey dude, why are going to bid $40 for that ipod on ebay when you can buy it now at tweeker bay from cranster tony down the street for $10?
by HOT POCKET STOMPER May 27, 2010
Tweeker county is known as a small county in Minnesota famous for its meth users and puddle sluts. Aka: Meeker county Minnesota.
by not a meth head February 13, 2014