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The McDonald's 

When you buy the cheapest prostitute available and end up with gonorrhoea and regret
The morning after Luke Smith did The McDonald's,
Luke Smith: "Fuck"
The McDonald's by Shcok_Wrie0020 January 19, 2017

Mcdonald's 

Sandra and her family ate McDonald's everyday for breakfast lunch and dinner for a year. They all now have diabetes!
Mcdonald's by JewishDolphin January 3, 2008

McDonald's 

Restaurant whose mascot is a pasty-white pedophile with a red afro and whose current advertising campaign is an anagram of "Ailing Vomit". Destroyer of cultures, exploiter of peoples and a key player in the cause of one of the world's greatest killers.
McDonald's: Satan's favourite dish.
McDonald's by Andrew B June 11, 2006

mcDonald's 

A shitty, unhealthy fastfood restaurant that most Americans love to eat. The biggest fastfood franchise in the world. The spread of McDonald's in other countries also symbolizes the spread of American way of thinking, that is rationally break down things into standard procedures.
McDonald's burger has shit in it.
McDonaldization is a world-wide cultural invasion.
mcDonald's by Kythdsifek July 9, 2005

i'd hit it like a mcdonald's cheeseburger 

To have sex with (see "I'd hit it.")

Essentially making fun of the McDonald's commercial that uses "I'd hit it" with reference to a cheeseburger, which everyone knows is utterly misguided.
Wow look at that ass!
I'd hit it like a McDonald's cheeseburger.

McDonald's 

A restaurant chain that shamelessly whores itself to minorities, and evidenced by their latest "Ba-da-ba-ba-ba...I'm luvin'it!" campaign. The food is terrible with the exception of the fries, McChicken sandwich, and McFlurry.

Probably laces the food with nicotine.
As the last french fry disappeared forever beyond her event horizon, Sally accidentally saw her reflection in the window and shuddered at what she'd become. At that moment she realized there was only one logical course of action: she had to sue McDonald's.
McDonald's by Veldrimal December 14, 2004