A hot box is when you are in a room with a couple of people and you have to fart so you get up and close all the windows and then fart and piss everyone off.
Me and the guys were watching the game last night until I hot boxed them and we all had to leave the room.
The administration of illicit substances through the vaginal (or anal) cavities. Mainly powdered or liquid drugs that will be absorbed through the mucosal membrane.
The pros of this method include rapid response and a relatively painless delivery.
I couldnt even tell she was a meth head-she's been hot boxing!