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I.S.H. Syndrome 

There is really too much to explain here, so i'm just going to try and cover the basics. I.S.H. Syndrome, also known as "ish" syndrome, is an illness that certain females acquire sometime after their teenage years begin. The acronym stands for "i'm so hott." This is how it works. There are girls that get so much attention from guys, that throughout their teenage years they have everything handed to them. There are always guys throwing themselves at them, raving over their looks, or trying to hit on them constantly. Because of this, they hardly ever have to work for anything and develop a stuck-up attitude about themselves. Eventually they just become completely full of themselves and expect the attention, as anything less would be a shock to their system. So they continue to walk around with this attitude, feeding off of attention like a frog in a room full of flies. What can you do to treat this syndrome? Not much. Just treat them like they're nothing special and maybe they'll at least get a little hint. This might help a little bit, but a total cure is highly unlikely. They're basically goners. All you can do for these individuals really is pray... just pray.
"Stacie is so hott, but she's got a severe case of I.S.H. Syndrome. I'd never want to date her."

"Did you check out that new hottie?" "Yeah, but I hear she's got a serious case of Ish Syndrome." "Awh, eff that man. Nobody wants to deal with that."
I.S.H. Syndrome by Lukefrizzle December 14, 2011
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Slurping Syndrome 

A commonly diagnosed syndrome in which the affected person can't stop slurping. The patient feels great pleasure when slurping and feels the need to write out "slurppppppp." No cure for this disease has been found yet.
Hey what's up?
Nothing much?
SLURPPPPPPP (slurping syndrome)

Creepy Uncle Syndrome

Where a person is really nice and outgoing, but you always have the feeling that he/she is a creeper/pedophile/ect.
Dude, my gym teacher last year had some bad creepy uncle syndrome!
Creepy Uncle Syndrome by Neinman January 1, 2010

Winston Smith Syndrome 

Referring to the character Winston Smith from 1984, Winston Smith Syndrome is when a guy viciously hates a girl because he wants to fuck her and she is unavailable or just doesn't like him. This is referring to the relationship between Winston and his love interest, Julia, at the beginning of 1984, in which Winston wants to murder Julia who he believes she is an ardent Junior Anti Sex League member.
Boy: Ugh, I HATE that girl. She is such a shallow slut and only dates dumb jocks.
Girl: Uh huh.. Winston Smith Syndrome much?

Dark Souls Syndrome 

After hours of playing the masochistic gamer's favorite - Dark Souls, and ofcourse, dying and dying and dying and getting raped by that dragon on the bridge and dying and dying and dying and dying and dying...

Did I mention you die a lot in this game?

Anyway, after a while of playing Dark Souls, encountering seemingly impossible boss fights, losing thousands of souls over dying and even starting a new character because your previous one had shitty statistics, you start to become REALLY rude and mean to everybody due to the built up madness caused by the above reasons, and when you finally manage to get through and feel immense joy, the people you offended might not share your joy.

Remember kids: Dark Souls is bad for your mental health.
Frank: Hey Joey, wanna go out for some pizz--

Joey: OH FOR FUCK'S SAKE! CAN'T YOU SEE I'M TRYING TO KILL THIS BOSS!?

Frank: Geez! calm down! I think you might be developing the Dark Souls Syndrome!
Dark Souls Syndrome by Fruitfly September 13, 2012

Stockhomo Syndrome

The unconscious assimilation of camp mannerisms as a consequence of spending time with gay friends or engaging with gay culture.
"Brett spent the whole weekend watching re-runs of Will and Grace and suddenly he's obsessed with telling me which celebrities are in the closet."

"Sounds like a case of Stockhomo Syndrome."

Ashy Nigga Syndrome 

A very serious disease and incurable that Kim Namjoon of BTS has that causes him to look pale cuz we all know he's black :(
"Ay yo did you hear that Kim Namjoon has ANS?"
"What's ANS?"
"Ashy Nigga Syndrome."
"Damn. Sounds serious."