Manuel Share definition Flag A Mexican man, usually fat. He likes cuss at people and shove around people. Other than that, he is a sort of nice person. Hahaha look, That fat boy over there is laying on that kid and punching him. He must be a Manuel. Manuel by Beat the heat March 25, 2013 0 0 Get merch Get the Manuel mug. Buy Now — $32.95 See more merch