by RedHood115 February 1, 2017

by rdeba May 20, 2014

by Rent a car place January 31, 2019

Person with Down Syndrome, due to the fact the condition is caused by a person being born with 47 chromosomes instead of 46.
by Golden Hawk April 13, 2023

People who have extra chromosomes and are best friends. "Chromie" referring to chromosome and "homie"s referring to " people who are good friends and would die for each other".
People who have extra chromosomes and are friends are considered extra chromie homies. Yesterday, John and I went into the extra chromie homie room by accident.
by B4dg3r January 12, 2017

Autistic Child #1: I'm gonna shoot up the school
Autistic Child #1: You cool though.
Me: You my homie with an extra chromie man.
Autistic Child #1: You cool though.
Me: You my homie with an extra chromie man.
by Phiriz January 30, 2018

by aussieyak June 16, 2016
