Up Syndrome

Up Syndrome is when someone with Down Syndrome is high off weed

“Bro is he ok”
“Nah he’s having a bit of Up Syndrome”

by Wild Warren December 13, 2020

Pumped Up Kicks Syndrome

Dank ass music. Dark ass lyrics.

“Pumped Up Kicks” by Foster The People sounds like an upbeat song, but upon further examination, it is about a school shooting. Any song that has a happy tune, but dark lyrics has Pumped Up Kicks Syndrome.

by SB757 December 23, 2023

Up syndrome

When someone is so retarded they have "up syndrome" instead of down syndrome

yo mama so stupid she has up syndrome

by A_Walking_Meme June 18, 2019

Fingers Up Nose Syndrome

Fingers Up Nose Syndrome is a genetic disorder commonly found in 15 Year old Arma 3 Players where they sound like they have their fingers jammed up their nose. There is no known cure for this disorder but there is hope for when Arma 4 gets released.

Wow these kids have a bad case of Fingers Up Nose Syndrome.

by Geeezzz1231 July 31, 2019

up syndrome

when you have so much down syndorme it inverts itself

"jozlen sussy jol" up syndrome

by jolzen December 1, 2022

Up Syndrome

When someone tends to hover above chimneys

Dolly has up syndrome, look at her hovering

by Dick Massive June 30, 2021

Up syndrome

you say it to insult someone

you don't have down syndrome you have Up syndrome

by MangoMane January 25, 2025