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.22

A .22 pistol.
"So I bust out my .22 and started laying down crew."
by Diego August 31, 2003
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22

a '22' is a nickname for a 22 millimeter semi-auto pistol you retards... they're small pistols that go for about 100 bills on the street... fits perfectly in jean pockets... perfect for provin a point to somebody
"i copped this hott chrome 22 piece for a buck las nite"

"my boy got 10 years in prison for jus bein found wit his 22 and some hollow tips in his pocket"
by jotz May 13, 2005
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22

I like this number.
You can also get this number by adding 11 and 11.
You can also find this definition by typing 2 twice on your keyboard in the search bar.
by ilike22 July 21, 2023
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.22

A small caliber hunting cartridge only capable of taking down small game. In a self-defense role, the .22LR cartridge has little stopping power and little stopping power. So, just because Ice Cube says it's cool, don't go out and buy one. The 9mm is the better choice in defending yourself. Although it at best is a crappy round for anything but rabbits, it can be used for maximum infection because if used wisely, a .22 will not leave an exit wound.
Wow, you're gonna use a .22 to knock the bank over? Even the bank teller will whoop your ass!
by Spiku June 24, 2004
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22

a 22cm cock
Oscar has a 22
by dee-dubz November 12, 2009
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.22

a small gun that does little harm when the standard firing function is used, but does a good deal of damage if it is used to bludgeon someone's eye areas.
Whatever you do, just don't use the deuce deuce on me. You might dent my soda can.
by I Dance Jigs March 12, 2003
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22

VTA Line 22, a bus route that goes between Menlo Park and eastern San Jose (more specifically, Eastridge Mall) along El Camino Real, The Alameda, Santa Clara Street, Alum Rock Avenue, King Road, and Tully Road. It is one of the longest and most well-known bus routes in the South Bay region of the San Francisco Bay.

The 22 runs more frequently than any other bus route--buses show up every 10-15 minutes during the day, and the route operates 24/7. Additionally, it is the only bus route that uses bendy buses.

Unfortunately, because of the 24/7 schedule, bums and smells reminiscent of shit are pretty common, especially at night. As a result, the 22 has come to be known as "Hotel Deuce Deuce," "the Felon Express," among others.
I stepped onto the 22, and got out in 3 seconds flat. I'd rather take a cab home.
by Raymoo November 1, 2007
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