The source of all men's problems. THis bitch has ruined all mens lives by teachin women to be more independent and to basically fuck up mens lives. SHE MUST ME STOPPED!!
by Giants8189 June 26, 2005

When you finish in your significant others face while screaming "you get it in the face! You get it in the face!"
by PhoenixFury36 May 18, 2016

When you finish in your significant others face while screaming "you get it in the face! You get it in the face!"
Oh my god, it was so hot when my boyfriend and I had sex, then he surprised me with the Oprah Winfrey.
by PhoenixFury36 May 18, 2016

by golden pineapple August 27, 2018

Better known as OWN, this is a channel exclusively dedicated to 24/7 daytime programming, but is subject to change in the future, as it is still in it's infancy. Also serves as an early sign of Oprah's plans of dominating the world taking place.
Person A: Hey, Oprah Winfrey has her own network now called the Oprah Winfrey Network.
Person B: Word? You won't catch me watching that shit.
Person A: True, but it won't be long now until you hear about an Oprah Winfrey country populated by nothing but middle-aged housewives.
Person B: Word? You won't catch me watching that shit.
Person A: True, but it won't be long now until you hear about an Oprah Winfrey country populated by nothing but middle-aged housewives.
by Tekkenfreek234 January 4, 2011

When a chick, who is usually fat, gets skinny, then fat than skinny again. But she always ends up fat for a while, suffering from not being able to stay skinny. Named for Oprah's constant wait loss and eventaul regain.
Ted: That cow Hillary is fat again! She was skinny last week!
Pat: Poor bitch has Oprah Winfrey's Disease! She can't keep the wait off.
Pat: Poor bitch has Oprah Winfrey's Disease! She can't keep the wait off.
by APT October 13, 2005
