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Oprah Winfrey 

1954-, television talk show host, actor and all-around American success story.
"Oprah Winfrey is starring in four upcoming movies!"

"Doesn't surprise me, Oprah's a legend."
Oprah Winfrey by golden pineapple August 27, 2018

Oprah Winfrey 

A snake s stupid lying backstabbing hoe who gave two frauds a platform who haven’t been abused she wouldn’t be this big at all if it wasn’t for Michael Jackson if she haven’t interviewed him
Oprah Winfrey by Dooche1456 March 6, 2023

Oprah Winfrey Network

Better known as OWN, this is a channel exclusively dedicated to 24/7 daytime programming, but is subject to change in the future, as it is still in it's infancy. Also serves as an early sign of Oprah's plans of dominating the world taking place.
Person A: Hey, Oprah Winfrey has her own network now called the Oprah Winfrey Network.

Person B: Word? You won't catch me watching that shit.

Person A: True, but it won't be long now until you hear about an Oprah Winfrey country populated by nothing but middle-aged housewives.

Oprah Winfrey's Disease 

When a chick, who is usually fat, gets skinny, then fat than skinny again. But she always ends up fat for a while, suffering from not being able to stay skinny. Named for Oprah's constant wait loss and eventaul regain.
Ted: That cow Hillary is fat again! She was skinny last week!
Pat: Poor bitch has Oprah Winfrey's Disease! She can't keep the wait off.
Oprah Winfrey's Disease by APT October 13, 2005

oprah winfrey orgy 

When you have an std and you have an orgy-
AND YOU HAVE AIDS! AND YOU HAVE AIDS! AND YOU HAVE AIDS! EVERYBODY GETS AIDS!

Oprah Winfrey orgy
oprah winfrey orgy by WITTYMOFO December 4, 2013