1. Toe up is a term made popular in the teen dramady, "Clueless." Dione says that Ty is "... toe up; our stock would plummet." Meaning that Ty is lousy and useless, not to mention detrimental to social status. 2. Also can be taken as "upside down."
1. That guy is toe-up. Don't hang with him.
2. I was so toe-up for Paul, I can't believe he likes Shelly instead.
2. I was so toe-up for Paul, I can't believe he likes Shelly instead.
by Dude November 23, 2004

by speculatrix November 28, 2010

by jeepdude44 June 14, 2015

this term is used to describe a physical position; while it could be used to describe anyone who is sleeping, it is most appropriately used to describe a condition achieved earlier than normal in the evening, perhaps after happy hour or some alternative form of mood management
"Hey man I called you last night around 10 to see if you wanted to go out," "Ahh.. damn man, by 10 o'clock Ize already ten toes up."
by Robbie Dee July 23, 2008

by MC R.A.B January 2, 2009

by Lil boop August 28, 2006

someone who is just ridiculously ugly from toe to head; also could reference the cleanliness of one's domicile.
by Anonymous February 6, 2003
