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A safe word used when one is uncomfortable. Once the safe word is used all others must leave the user over the alone. This applies to men, women, all physical proximity offenders, and "gender undiscriminating" sexual predators.
Ethan: "Hey Mike, you look cute"
-Ethan then touches Mike leg-

Mike: "Muskrat!"
-Ethan sighs and moved a couch seat away, and cross his arms upset-
Muskrat by 5725 July 18, 2012
What you call the most attractive person in your group of friends. Usually is perfect in every way and everyone is jealous.
"See that girl over there who is so beautiful and smart and perfect?"
"Yeah, she is a definitely a muskrat, dude!"
"AGREED!"
Muskrat by klasjdhladksjhfaldk December 14, 2013
A form of torture, varying from forceful sexual activities, to beating the victim mercilessly with eggplant shaped objects, or making them watch pornography of their grandparents/parents. After a muskrat takes place it usuall takes 2 weeks to recover if you survive. YOU DON'T WANT A MUSKRAT!!
Dude did you hear? Riley was given a horrible muskrat, and they found him in the bathroom traumatized, and shaking while whispering "didn't want to go first"
Muskrat by Muskratman March 30, 2015

Muskrat. 

Often known as slang for someone who plays too much world of warcraft, and tells their parents to get their router.
Ray: "Andrew is such a Muskrat."
Ken: "Yeah, he should probably get off his ass and get onto real life."

Muskrat's Nest

A Muskrat's Nest is defined as completely filling the toilet bowl with paper, even until the toilet paper is high and dry above the bowl line, and then defecating on top of the giant pile of toilet paper. A properly built nest can usually only be removed by the use of a spade shovel, as flushing at that point would prove all but impossible. By keeping the muskrat on top of the nest and not in the water, the vile stench of the muskrat can be allowed to permeate the entire venue. The muskrat's nest is intended as a practical joke, or as revenge for having been muskrat-nested. A Muskrat's Nest must be built with caution, as they are illegal in most states.
Rob: Hey Jake, the service at this restaurant totally sucks ass!

Jake: Yeah, you should totally go build a Muskrat's Nest in the men's room!

Rob: Fuck yeah! That'll teach 'em! In fact, I'll even do it in the lady's room!

Muskrat love 

Went Tenille hasn't showered in a week, but the Captain's launching anyway.
Suzy didn't want to make love cuz she didn't smell pretty, but Sam told her it's all good under the hood when it's "Muskrat Love".
Muskrat love by Melow1d December 11, 2016