Usually used in conjunction with "nizzle", both words where invented by rapper Snoop Doggie Dogg. Instead fo saying what was used until then, "Fo' sure, my nigga.", he created the phrase "Fo' Shizzle my Nizzle"
by Major Mandess August 11, 2003

by Big Smoke Dogg November 25, 2003

For sure; Often a word used by teenage white dip shits (see wigger) that try to have street cred, often used with cojunction with "nizzle"
Poser: You want subway?
'nother poser: Fo shizzle my nizzle in the hizzle off the Chain!
Normal person: Shut the hell up.
'nother poser: Fo shizzle my nizzle in the hizzle off the Chain!
Normal person: Shut the hell up.
by Posers suck my balls October 21, 2007

For sure; of course; I strongly agree. Basically, it means "For sure" or "Fo' sho'" in that Snoopizzle language thing.
-Word!
-Fo' shizzle!
-Fo' shizzle!
by the sane maniac October 2, 2004

by br December 11, 2003

by D Roc32092 May 16, 2006
