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Middle Child Syndrome 

an emotional scarring condition.
Middle children are known for ending up with the things that are too big for the baby in the family and too small for the oldest.
it is a known fact the youngest and oldest are treated differently than the middle child for the oldest is the first child aka favorite
and the smallest is the baby aka the last child known for getting whatever they desire because they are the "baby"

Middle Children sydrome includes
neglect, forgotten dates, and sometimes in bad cases forgetting they even exist.

i lived through this condition,
it is not fatal
just difficult.
a first born: OH i just got this GREAT new car!
a middle child: oh...i have to wait until my sister wrecks hers...then i can have that and they will get her a new one
a first born: oh Middle Child Syndrome, i see.
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Carpool Tunnel Syndrome 

When you are carpooling and you enter a dark tunnel and get that "uneasy feeling" as you sitting next to someone you don't "Really" know.
On the way out of Boston, Sally got Carpool Tunnel Syndrome from the new guy John.

ugly duckling syndrome 

When a person who used to be somewhat awkward and not attractive, though not necessarily unattractive, becomes extremely beautiful. Because this person used to be unattractive, bitter and jealous people assume they are emotionally damaged and scarred. Hence, they believe the aforementioned beauty is mentally demented, while they themselves are sympathetically retarded.

Ugly Duckling Syndrome is an excuse to undermine the physical and inner attractiveness of a blossomed beauty.
"Wow! That girl used to be really awkward! What happened! I'm sure she MUST have done some kind of plastic surgery to get that face. I guess she's really insecure then, and she probably has ugly duckling syndrome."

"No you dipshit, she just went through puberty."

Man-Child Syndrome 

Not quite a man, not quite a child. Stuck somewhere in between. Has memories repressed from when he was a child
TA: He has man-child syndrome

TA: You know, he's not quite a man, not quite a child

Student: Oh Kinda like Zac Efron?

Nascar Syndrome 

When a joystick of any kind will only turn left.

Could be used for other things I suppose
Don't use that controller, it has Nascar Syndrome.

FFK Syndrome or Former [Fat Kid] Syndrome 

A person who, in the past was fat and/or utterly unattractive, but now is considered attractive by society, yet still retains the mental, and emotional status of a fat kid and therefore does not understand social cues.
"Jane may be hot now, but she still suffers from FFK Syndrome or Former Fat Kid Syndrome"

Male Loneliness Syndrome 

Male Loneliness Syndrome, known as MLS, is a heterosexual male mental disorder caused by constant rejection by women.
Jerry has Male Loneliness Syndrome since he no longer bothers to try dating women because they constantly reject him because he isn't good looking and rich enough.