The feeling of dread one feels when they finish a movie, show, book etc. knowing that the story is over.
by Doodope March 1, 2021

It's a made up fatigue where your sanity is being destroyed from repetitively texturing Splatoon models for two days.
by okmrsavage September 17, 2022

The exhaustion you feel from having to speak to your neighbors every time you go outside. The moment you step outdoors, they want to chat when you want to chill out or work in the yard. neighbors, frontyard, backyard, annoying neighbors, neighbors from hell, next-door neighbors, neighborhood, home, picket fence, fence
Every Saturday, I never get any work done because 4 or 5 of my neighbors come over to talk about their families, kids and jobs. I've got serious neighbor fatigue.
by joecoolthefool July 8, 2017

by Leonai_art February 21, 2020

When you are doing late night raiding and you feel really tired, uncomfortably warm, and a little sickly. Normally attributed to WoW.
"Bob stayed up late on WoW and got raider's fatigue... he looked like shit just before crawling into bed."
by Honath November 30, 2013

When one becomes tired from interacting with to many people, or from to having a conversation for too long. Especially common in with introverts
“After dealing with all of those customers I feel people fatigue coming on”
Or
“Hey, why did you leave the party?”
“Oh, I just got people fatigued.”
Or
“Hey, why did you leave the party?”
“Oh, I just got people fatigued.”
by TyJaxx August 20, 2022

Felling tired or fatigued by a common internet joke, saying, photo, or gif. (Meme.) Someone experiencing Viral Fatigue may feel like a meme is "beating a dead horse." The meme may be old, common, and overused, resulting in it not being humorous.
by racergamer February 22, 2015
