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Uncle Jesse 

When two men are caught rubbing their anuses together.
Uncle Jesse saw the Duke boys rubbing their anuses together down by the crick. Uncle Jesse masterbated while Danny Tanner and Joey rubbed their anuses together.
Uncle Jesse by Last_Boy_Scout November 13, 2011

Uncle Jesse 

A bearded racist from the backwoods of Georgia who guzzled Daisy's huckleberry pies like it ain't no thing. He was played by Denver Pyle, the father of John Stamos. Denver Pyle died a while ago; he died of lung cancer. It probably sucked. He was from Methune, Massachusetts
Denver Pyle? You mean Mr. Methune?
Uncle Jesse by T Dog Jenkins June 11, 2004

uncle Jesse style 

To sit backwards in a chair so that your stomach is against the chairs back. You may or may not cross your arms and put them on top of the chair's back. Used when uncle jesse'in it or just being cool.
I wanted to look cool today so I sat uncle Jesse style. Then everyone copied me.
uncle Jesse style by hoss cat October 22, 2007

uncle jesse'in it 

To be sweet and caring. To offer advice as if you are the only one who knows what you need to hear. To help someone with their problems. If you are truly uncle jess'in it then when someone does something to you or someone you know, you don't tell. To be cool while doing all this.
I have been Uncle Jesse'in it with everyone in my family today. My sister broke my TV but since she is going to replace it I don't see a reason for anyone to know.
uncle jesse'in it by hoss cat October 22, 2007

uncle jesse and the oslen twins 

man that band sounds like uncle jesse and the olsen twins

uncle jesse and the olsen twins 

less better than Ratslayer and the crackerjack horse killers!
Ratslayer and the crackerjack horse killers are infact not uncle jesse and the olsen twins.