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A Pronoun used to describe one of 5 individuals, namely, The Spice Girls: Melanie "Scary Spice" Brown, Melanie "Sporty Spice" Chisholm, Geri "Ginger Spice" Horner (nee Halliwell), Emma "Baby Spice" Bunton, or Victoria "Posh Spice" Beckham (nee Adams-Wood)
"Did you see The View had a Spice on today, yeah, Scary Spice. She so gorgeous."

"Did you hear? All 5 Spice's are reuniting this 2018?"
Spice by SoWeirdBoy March 3, 2018
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This girl is a spice meaning she’s hot
Spice by Spicy 🌶 November 13, 2018
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Like tea, spice is used to describe that something is hot or that you didnt expect it.

It can also be used when you are about to tell a story.
"Let me tell you this spice"

"Girl spice"

"You spicy"
A synthetic marijuana that was legal until March 2011. Unfortunately, those jokers at the DEA caught on and banned the main stuff that's in it, so its not legal any more. K2 can have the same ingredients as spice, so its probably banned too.
Spice by free-to-beeee May 30, 2011
Term (1970s) used for sweets in Yorkshire, northern England.
I'm going to get some spice from t'shop = I intend to purchase some confectionery.
spice by D. Speakman August 21, 2005
bf "I learned something new on the Spice channel."
gf "really show me..."
spice by mr. filler July 15, 2004
2-CI, aka 2,5-dimethoxy-4-iodophenethylamine, a short acting synthetic psychedellic compound. Can be taken orally or snorted.

Often confused with mescaline, therefore it is sometimes refered to as "synthetic mescaline".

the name comes from the fictional conciousness expanding drug "spice" found in the book Dune, by Frank Herbert and the Star Wars films.
"They have been tripping on the spice all night."