s.i.s.

An acronym for Sudden Insanity Syndrome

Joan Crawford had a lot of experience with S.I.S. moments.

by Candide March 6, 2008

S.i.S.

Shit is Situational.
(forum speak)

Person A: (When z1,) X > Y.
Person B: But when z2, Y > X!
Person C: *facepalm*C'mon guys, S.i.S.

by ShamayaXI September 12, 2009

S.I.S.

Self-inflicted stupidity. An injury that you caused to yourself by an act of stupidity.

Friend 1: How did you get that cut?

Friend 2: I was running with scissors down the stairs and my shoes were untied.

Freidn 1: Thats some serious S.I.S.

by Ahseetz Mahpants January 10, 2009

S.I.S

SIS is a school in summerside P.E.I where kids like to wipe shit all over the mirror in the guys bathroom for fun and where kids like to vape in the school bathroom what a lovely school

guy one "did you hear about S.I.S"
guy two "ya isn't that , school that likes to wipe shit on mirrors and vape in the bathrooms?"
guy one"ya exactly"

by shit picker November 29, 2019

S.I.

A Smelly Indian

Smelly Indians, or people with Turbans with unreal stench.

Manavpreet and Harpreet are such S.I.'s

by automatic.armadillo.42 May 14, 2022

S.I.

Smelly Indians

People from the country of India or Punjab who reek horrible stench.

Especially people with turbans.

Manavpreet and Harpreet are such S.I.'s.

by automatic.armadillo.42 May 14, 2022