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When embarking on a long-distance relationship LDR and each party has gone past the stage of being crazy for one another but have yet to meet in person. Normally this would be called 'fucked' but because you've not had the chance to fuck yet, you're 'pre-fucked' or 'prefucked'. Which takes into consideration the waiting period of time before you get to actually fuck.
Steve, while chatting online with Sally: "I'm totally prefucked for you!"

*****

John: "Man, Chris is dissing us again because of that girl he's talking to online!"

Bill: "Yeah man, he's totally prefucked about her."

*****

Tina talking to Lisa: "Girl, why isn't Melissa hangin' out?! Is she prefucked with that guy she met on that dating site?"
prefucked by Jersey_in_Autumn November 22, 2011
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that high/sober feeling that you get whenever the weed or edibles don't hit as hard as they usually do
adam: "yo did that toke hit yet?"
kyle: " nah bruh i'm prefucked right now"
adam: "ah shit thats the worst"
prefucked by shlongdicknibba April 26, 2020
originally came from the word perfect and fuck.
good at fucking !
peter perfucked it!
Perfucked by globa! February 12, 2007
When something is both Perfect and Fucked at the same time
Person 1: I managed to get a ball in the hole with an awesome shot in pool, but then the white ball went in
Person 2: Mate, that’s perfucked